Cell Signaling
Introduction: The Experiments of E.W. Sutherland
Read the E.W. Sutherland manuscript and watch the cleverly produced video.
Need more assistance? Want College Practice? Try this video.
Credits:
- manuscript:
- Cori, C.F. (1978). Earl W. Sutherland: 1915 - 1974. National Academy of Sciences, Washington, D.C.
- clever video:
- Sedgwick, W. & Wilcox, M. (2015). Earl Sutherland Experiment. Retrieved 20 January 2015 from: https://www.youtube.com/watch?v=GpeOHz4RPic
G-Protein signaling (above image from commons.wikimedia.org). In this image we see an inactive G protien (G) embedded in the cell membrane along with a receptor (R) and an enzyme (E). When a signaling molecule (hormone) enters the active site on the receptor, the receptor is able to activate the G-protein (GDP becomes active GTP). The message from the signal molecule (hormone) is sent to the G-protein and the hormone is released. The G-protein moves along the membrane to the enzyme which is subsequently activated and receives the message from the G-protein. The enzyme elicits a cellular response.
Cell Suicide (Apoptosis): A Heroic Death
Read the NIH article. Get out your tissues as this is a story of noble heroism and concern for the greater good. Nature Rocks. Life Unleashed...
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